PAMINA-NBP is a web-based hardware and software platform specifically conceived to gather, manage, retrieve, show and process data and metadata in a modern neuroimaging laboratory. The system is targeted for the field of clinical research on human brain functions (from acquisition to final processing), but it can be used as well in the clinical and diagnostic field. PAMINA-NBP is an example of scientific and technological knowledge transfer in clinical research. PAMINA-NBP enables high-level data processing and allows data visualization depending on user qualification and professional objectives.
It has been designed in a highly proven operative context and it presents a lot of interesting technological innovation aspects. Among these, we must cite the multimodal analysis environment integrated with an intelligent repository that allows the storage of all information at any processing step, from raw data to final results.
PAMINA-NBP was funded by Regione Lazio under grants POR-FESR 2014–2020 RU-2014-1092 (2015-2018) and A0320-2019-28189 (2020-2022).
In particular, the ongoing grant (NBP) will integrate various improvenments in the platform, including AI capabilioty.
The aims of the NBP project is to create a unified platform for data management and archiving services, multimodal analysis with a transversal and longitudinal character designed for clinical research applications, and to support multicentric collaboration in neuroscience.
The objectives to be achieved within the projectcan be divided into:
- Realization of the industrial product
- Creation of an innovative, effective and safe IT platform to support neuroscience.
- Research objectives
- Investigate the automatized application of Artificial Intelligence tools to neuroimaging.
- Development of quantitative MRI methods for the characterization of microstructural damage and brain function in pathological conditions
- Social Objectives
- Creation of a platform to support the fight against neurodegenerative diseases.
The collaborative tools will facilitate access to remotely acquired research products, in order to overcome some of the limitations of neuroscience research in Lazio, including the dispersion of research infrastructures throughout the territory and the lack of attractiveness to researchers abroad.
NBP platform has a unified interface for collaborative data analysis. The infrastructure includes a data transmission and storage infrastructure and a grid processing infrastructure that integrates information fusion, automated analysis and multiparametric classification algorithms based on artificial intelligence.
The key feature of the latter subsystem is that it can be modified, developed and integrated by users, while integrating mechanisms for the protection of intellectual property and privacy that allow the selective sharing of data and algorithms resulting from scientific and / or commercial collaboration.
The project is a collaboration between Centro Fermi, ISS, Sapienza and PJC.